Bone fracture is a global public health issue, which relates with an increasing longevity of human life, and poses a serious economic burden. In every age cohort fractures lead to health losses and high health-care costs. Despite the long history of fracture’s curation, medical care system still faces with complexities in fracture healing, especially if they associated with an osteoporosis. The purpose of the study given was to investigate the potential of osteoinductive preparation and evaluate bone density at the femur fracture site with local introduction.